The Next-Generation Medical Hypergraph & Pedagogical Operating System

Ground Medical Education in Real Evidence.

Meda Knowledge Core bridges raw PubMed biomedical literature, GRADE evidence-based knowledge graphs, and an AI-augmented course authoring workspace with pluggable local & cloud LLMs.

Pathology Workspace · AVC Ischémique & Thrombolyse IV
Hypergraph Synced
Markdown Editor (Phodoc)Live Word Indexing

# Prise en charge initiale de l'AVC Ischémique aigu

L'administration d'altéplase IV (rtPA) dans la fenêtre des 4h30 réduit significativement le handicap fonctionnel à 3 mois (mRS 0-1).

Multi-LLM Brainstorm BarOllama Local / Llama 3.3

"Générer 3 questions de validation clinique de niveau Bloom 4 sur les contre-indications..."

Meta-Analysis GroundingPMID: 25106063
GRADE: High Certainty (A)

The Lancet Meta-Analysis (9 RCTs, N=6756)

Odds Ratio1.75 [1.47-2.08]
p-value< 0.0001
I² Heterog.0%

Modular Architecture

Built for Clinical Rigor and Academic Precision

EVIDENCE ENGINE

Medical Hypergraph Core

Ingests PubMed literature and breaks down complex clinical findings into n-ary Statements connecting Class A–E Atoms, bounded by clinical and epidemiological contexts.

PEDAGOGICAL SUITE

Phodoc-Grade Course Editor

Advanced dual-pane Markdown & PDF course creator with real-time token highlighting, dynamic Table of Contents, and multi-format DOCX/PDF exports.

MULTI-LLM COPILOT

Pluggable Brainstorming Bar

Directly plug into your model of choice — whether cloud LLMs via OpenRouter (Claude 3.5, GPT-4o) or 100% private local models running on Ollama & Llama.cpp.

META-ANALYSIS INDEXER

Instant Evidence Grounding

Select or highlight any clinical term to query systematic reviews, meta-analyses, forest plot statistics (RR, OR, I²), and insert verified citations on demand.

Multi-Tier RBAC

A Complete Hierarchy for National & University Healthcare

MKKC-V3 implements an 8-tier role architecture natively supporting Country Admins, Deaneries, Faculty Professors, and Residents.

Country Administrator

National Scale

Configure regional clinical guidelines (HAS, WHO, NICE), ICD-11 ontology baselines, and pedagogical criteria across universities.

Institution & University Admin

Faculty Tenant

Oversee medical faculties, hospital departments, residency quotas, and curriculum progress with unified RBAC.

Professor & Course Author

Course Creator

Author clinical courses with the Phodoc markdown editor, multi-LLM brainstorming (OpenRouter & local Ollama), and PubMed meta-analysis linking.

Clinical Validator

Evidence Peer Review

Audit automatically extracted Atoms and Statements, verifying GRADE evidence levels and clinical confidence scores.

Authoring Redefined

Any LLM of Choice: Local Llama, Ollama, or OpenRouter.

Empower medical professors to brainstorm, draft curricula, and synthesize complex clinical guidelines with complete freedom over their AI infrastructure:

  • 100% On-Premises Privacy: Connect local Ollama or Llama.cpp instances directly for sensitive hospital data.
  • Word Highlighting to Meta-Analyses: Click any disease or treatment token to preview GRADE certainty and forest plots.
  • Automated Table of Contents & Multi-Format Exports: Generate structured outlines and download publication-ready PDF and DOCX files.
Editor Intelligence Drawer
DOCX ReadyPDF Ready
TABLE OF CONTENTS (LIVE OUTLINE)
1. Définition et Épidémiologie (A:PATH:AVC)
1.1 Diagnostic Différentiel et Score NIHSS
1.2 Thrombolyse IV vs Thrombectomie Mécanique
2. Niveaux de Preuve GRADE & Recommandations
Highlighted Entity: "Altéplase IV"Linked to Class B: Molecule

Indexed in 4 Systematic Reviews with 9 Meta-Analyses. Absolute risk reduction of 9.8% for disability at 90 days.

Literature Ingestion

From PubMed Abstracts to Verified Clinical Knowledge

1. CIM-11 Hierarchy2. PubMed Automated Crawl3. Section Chunking4. Embedding Vectors5. Class A–E Atomisation6. Link Types L1–L127. N-Ary Statements8. Pedagogical Course Generator